Aminobenzoic acids and derivatives
eMolecules 27466-83-7 | 4-Bromo-N-methylbenzamide | Synthonix - Stock | MFCD00462943 | 214.062 | C8H8BrNO | 97.000 | CNC(=O)c1ccc(Br)cc1 | 10g | 459660520
4-Bromo-N-methylbenzamide | Synthonix - Stock | 27466-83-7 | MFCD00462943 | 214.062 | C8H8BrNO | 97.000 | CNC(=O)c1ccc(Br)cc1 | 10g | 459660520
eMolecules 3544-24-9 | 3-Aminobenzamide | Key Organics/BIONET | MFCD00007989 | 136.154 | C7H8N2O | 98.000 | NC(=O)c1cccc(N)c1 | 9mg | 564356345
3-Aminobenzamide | Key Organics/BIONET | 3544-24-9 | MFCD00007989 | 136.154 | C7H8N2O | 98.000 | NC(=O)c1cccc(N)c1 | 9mg | 564356345
Aobchem 2 6-Dichloro-3-methylbenzamide | 97% | CAS 1803835-81-5 | C8H7Cl2NO | 250mg
2 6-Dichloro-3-methylbenzamide | 97% | CAS 1803835-81-5 | C8H7Cl2NO | 250mg
eMolecules 106037-36-9 | 4-amino-3-methylbenzamide | MFCD08061918 | 5g
Ambeed | 1-(4-Methoxybenzyl)-4-(4455-tetramethyl-132-dioxaborolan-2-yl)-1H-pyrazole | 1g | 572945307 | A340561 | 1105039-88-0 | MFCD16877287 | 314.190 | C17H23BN2O3
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Medchemexpress LLC 4-methylbenzamide oxime | 19227-13-5 | MFCD00019952 | 99.2% | 150.18 g/mol | C8H10N2O | 25 G
4-Methylbenzamide oxime (CAS 19227-13-5) is a white to off-white solid used as a model benzamide oxime and as a substrate for mitochondrial amidoxime reducing component (mARC) enzyme reduction in biochemical assays. It is supplied at high purity and should be stored cold according to handling instructions in the SDS.
- Model substrate for mARC enzyme assays
- High purity (99.17%)
- Molecular formula C8H10N2O; molecular weight 150.18 g/mol
- White to off-white solid
- Recommended storage: powder at -20°C (up to 3 years) or 4°C (up to 2 years)
Medchemexpress LLC Exatecan (mesylate) (GMP) | 169869-90-3 | 531.55 | 100 MG
Exatecan mesylate (DX8951f) GMP is a GMP-class Exatecan, a DNA topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
- DNA topoisomerase I inhibitor
- Potent antitumor activity against human tumors in vitro and in vivo
- Inhibits tumor growth in various cancer cell lines
- Prevents lung metastasis in orthotopic implantation mouse models
Medchemexpress LLC Tetrindole mesylate | 170964-68-8 | 99.9% | 390.54 | C21H30N2O3S | 1 MG
Tetrindole mesylate is a research reagent that acts as a selective monoamine oxidase A (MAO A) inhibitor used in biochemical and pharmacological investigations of MAO-A activity and antidepressant mechanisms. It is supplied as a solid mesylate salt with high purity and is intended for laboratory research use only. Recommended storage: -20°C sealed and away from moisture; in solvent: -80°C (up to 6 months) or -20°C (up to 1 month).
- Selective MAO-A inhibitory activity for mechanistic and pharmacology studies.
- High purity (99.93%) suitable for analytical and preclinical assays.
- Solid form for accurate weighing and formulation.
- Contains CAS number 170964-68-8 for unambiguous identification.
- Recommended cold storage to preserve stability.
Medchemexpress LLC Ibutamoren Mesylate | 159752-10-0 | 99.86% | C28H40N4O8S2 | 1 G
Ibutamoren Mesylate (MK-677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR) agonist. It is an orally active growth hormone (GH) secretagogue.
- Potent, non-peptide growth hormone secretagogue receptor (GHSR) agonist
- Orally active growth hormone (GH) secretagogue
- For research use only
Medchemexpress LLC Dabrafenib (mesylate) | 1195768-06-9 | 99.9% | 615.67 | 50 MG
Dabrafenib Mesylate is a potent and selective Raf kinase inhibitor with IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively. It is intended for research use.
- Inhibits over 90% of cell growth in NRAS mutant clones
- Reduces S6P phosphorylation in A375 cells
- Suppresses PolyP-mediated vascular barrier permeability
- Downregulates HMGB1-dependent inflammatory responses
- Enhances the expression of cell adhesion molecules (CAMs) in human endothelial cells
Medchemexpress LLC Carbamimidothioic acid, 3-[3-[2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl]propyl ester, methanesulfonate | 138489-18-6 | 99.6% | 553.65 | 100 MG
Ro 31-8220 mesylate is a potent PKC inhibitor that also significantly inhibits MAPKAP-K1b, MSK1, S6K1, and GSK3β. It shows no effect on MKK3, MKK4, MKK6, and MKK7. This compound can inhibit the expression of MKP-1, induce the expression of c-Jun, and activate JNK, demonstrating pharmacological properties independent of PKC. It also directly suppresses voltage-dependent Na+ channels and exhibits neuroprotective qualities.
- Potent PKC inhibitor with low nanomolar IC50s for various PKC isoforms
- Significantly inhibits MAPKAP-K1b, MSK1, S6K1, and GSK3β
- Can inhibit MKP-1 expression and activate JNK
- Directly suppresses voltage-dependent Na+ channels
- Neuroprotective against paraoxon-induced neuronal cell death
Medchemexpress LLC CEP-28122 (mesylate salt) | 2070009-30-0 | 99.9% | 635.17 | 100 MG
CEP-28122 (mesylate salt) | 2070009-30-0 | 99.9% | 635.17 | 100 MG
Medchemexpress LLC Cep-28122 (mesylate salt) | 2070009-30-0 | 99.9% | 635.17 | 1 ML
CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally active ALK inhibitor with an IC50 value of 1.9 nM. It exhibits antitumor activity in experimental models of ALK-positive human cancers and possesses good pharmacodynamic and pharmacokinetic activity. This product can be utilized for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells.
- Potent, selective, and orally active ALK inhibitor with an IC50 value of 1.9 nM.
- Exhibits antitumor activity in experimental models of ALK-positive human cancers.
- Possesses good pharmacodynamic and pharmacokinetic activity.
- Can be used for the study of ALK-positive anaplastic large-cell lymphoma (ALCL), non-small cell lung cancer (NSCLC), and neuroblastoma cells.
Medchemexpress LLC Pritelivir mesylate | 1428333-96-3 | C19H22N4O6S3 | 100 MG
Pritelivir mesylate is an inhibitor of the viral helicase-primase complex. It demonstrates antiviral activity both in vitro and in animal models of herpes simplex virus (HSV) infection, effective against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2).
- Inhibits viral helicase-primase complex
- Exhibits antiviral activity against HSV-1 and HSV-2
- IC50 of 0.02 μM against HSV1-2
- For research use only
- Purity of 99.33%
- Appearance is solid
- Color is white to off-white